Survival-associated meQTLs across different cancer types
We identified 23,432 meQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
---|---|---|---|---|---|---|---|---|---|
LGG | rs9926961 | chr16:8709711 | A/G | 4.07E-5 | 509 | 9.93 | 17.58 | 24.03 | KM Plot |
LGG | rs9928374 | chr16:67811930 | A/G | 7.52E-12 | 509 | 6.47 | 30.47 | 21.7 | KM Plot |
LGG | rs9929335 | chr16:8710085 | A/G | 2.17E-7 | 502 | 8.17 | 17.2 | 24.05 | KM Plot |
LGG | rs9935332 | chr16:10848843 | A/G | 2.23E-5 | 502 | 23.53 | 20.32 | 8.17 | KM Plot |
LGG | rs9935855 | chr16:8709405 | C/A | 4.07E-5 | 509 | 9.93 | 17.58 | 24.03 | KM Plot |
LGG | rs9936296 | chr16:8709884 | C/T | 2.17E-7 | 502 | 8.17 | 17.2 | 24.05 | KM Plot |
LGG | rs9938862 | chr16:67723801 | T/C | 8.42E-12 | 508 | 21.6 | 31.63 | 6.47 | KM Plot |
LIHC | rs10134935 | chr14:95037079 | T/C | 5.13E-5 | 363 | 17.18 | 24.9 | 21.13 | KM Plot |
LIHC | rs10139277 | chr14:95035060 | C/T | 7.15E-5 | 367 | 17.07 | 26.07 | 22.4 | KM Plot |
LIHC | rs10146582 | chr14:95037778 | G/A | 3.5E-5 | 365 | 17.32 | 26.1 | 15.27 | KM Plot |
LIHC | rs10148605 | chr14:57693793 | T/C | 1.43E-5 | 364 | 20.33 | 17.83 | 3.83 | KM Plot |
LIHC | rs10149354 | chr14:95038368 | C/T | 6.88E-5 | 365 | 17.33 | 26.1 | 15.03 | KM Plot |
LIHC | rs10164440 | chr2:240288363 | A/G | 1.72E-5 | 368 | 19.95 | 20.42 | 10.12 | KM Plot |
LIHC | rs10166161 | chr2:37190695 | A/G | 1.27E-5 | 359 | 20.4 | 13.2 | 8.73 | KM Plot |
LIHC | rs10182741 | chr2:37165765 | C/T | 1.16E-5 | 365 | 20.5 | 12.17 | 8.73 | KM Plot |